Carlos Leandro Freites

Seeking rhythmic patterns in microglial cells within the circadian pineal gland from male rats

This study examines microglial morphology and function in the rat pineal gland across the light:dark cycle, finding age-related changes in rhythmicity and potential impacts on melatonin production.

Spatio-temporal dynamics of nuclear CREB1: what does it mean?

This study examines the spatio-temporal dynamics of nuclear CREB1 in rat pinealocytes, finding that its distribution varies across time and cell types, with increased dispersion at night.

Aβ promotes amyloidogenic processing of APP through a Go/Gβγ signaling

This study identifies a feed-forward mechanism where Aβ promotes APP processing via Go/Gβγ signaling, enhancing Aβ production and suggesting gallein as a potential therapeutic target.