Pharmacology & ToxicologyJournal of Medicinal ChemistryPeer-reviewed
Optimization and Characterization of SHIP1 Ligands for Cellular Target Engagement and Activity in Alzheimer's Disease Models
Cynthia D. Jesudason, Claudia Rangel‐Barajas, Colin J Beach…·Timothy I. Richardson
This study identifies SHIP1 ligands with brain exposure and in vivo activity in Alzheimer's models, showing target engagement and reduced neuroinflammation.
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