Constrained template matching using rejection sampling
Valentin J. Maurer, Lukas Grunwald, Dante Marvin Kennes, Lea Dietrich, Jan Kosiński
This paper introduces rejection sampling to improve macromolecular complex detection in cryo-electron tomography by incorporating biological constraints, achieving performance comparable to deep learning methods without annotated data.
bioRxiv · Jun 10, 2025 · PreprintBiophysics