Lea Dietrich

This paper introduces a combined MSI and cryo-ET pipeline for reliable single-cell classification in cryo-ET samples, enabling post-acquisition cell identification and classification.

The paper identifies a new mitochondrial morphology in yeast called Ringo that enhances respiration by ensuring proper OXPHOS complex assembly.

This paper introduces rejection sampling to improve macromolecular complex detection in cryo-electron tomography by incorporating biological constraints, achieving performance comparable to deep learning methods without annotated data.

The paper determines the in situ structure of mitochondrial ATP synthase in Polytomella algae using electron cryo-tomography, revealing six rotary positions and 21 substates of the F1 head.