Sedef Kollarik

Pharmacological enhancement of slow-wave activity improves cognition and reduces amyloidosis at an early stage in a mouse model of Alzheimer's disease

This study shows that enhancing slow-wave activity through sodium oxybate in early-stage Alzheimer's mice improves cognition and reduces amyloidosis, but not in older mice.

Novel murine closed-loop auditory stimulation paradigm elicits macrostructural sleep benefits in neurodegeneration

This study uses closed-loop auditory stimulation in mice to enhance slow-wave activity, improving sleep quality in Alzheimer's and Parkinson's disease models.

Natural age-related sleep-wake alterations onset prematurely in the Tg2576 mouse model of Alzheimer disease

This study shows that Tg2576 mice exhibit early sleep-wake alterations resembling aged controls before plaque formation, suggesting premature sleep deterioration in AD models.