Natural age-related sleep-wake alterations onset prematurely in the Tg2576 mouse model of Alzheimer disease
Sedef Kollarik, Carlos G. Moreira, Inês Dias, Dorita Bimbiryte, Djordje Miladinovic, Joachim M. Buhmann, Christian Rainer Baumann, Daniela Noaín
This study shows that Tg2576 mice exhibit early sleep-wake alterations resembling aged controls before plaque formation, suggesting premature sleep deterioration in AD models.
bioRxiv · Oct 25, 2021 · PreprintNeuroscience