Author

Ana Sastre-Perona

Hospital La Paz Institute for Health ResearchORCID 0000-0002-4502-3025Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein design· 1

Frequent Co-Authors

Álvaro García-GuedeiD· 1 shared Ana Arauzo-Cabrera· 1 shared Ana Belén Griso-AcevedoiD· 1 shared Beatriz CasteloiD· 1 shared Carlos Rodríguez‐AntolíniD· 1 shared Francisco NavasiD· 1 shared Inmaculada Ibañez de CáceresiD· 1 shared Isabel Esteban‐RodrígueziD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Álvaro García-GuedeORCID

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2 papers

Recent·Most cited

Epigenetic silencing of MAFG is a potential prognosis biomarker in lung adenocarcinomas

Álvaro García-Guede, Carlos Rodríguez‐Antolín, Ana Arauzo-Cabrera, Rocío Moreno-Velasco, Olga Pernía, Miranda Burdiel Herencia, Lucía Acero-Riaguas, Isabel Esteban‐Rodríguez, Silvia Sacristán, Raúl Torres-Ruiz, Sandra Rodríguez, Ana Sastre-Perona, Victor M. Gonzalez, Javier de Castro, Inmaculada Ibañez de Cáceres, Olga Vera

The paper investigates MAFG's role in DNA methylation remodeling in NSCLC, finding that MAFG methylation and protein levels are prognostic biomarkers, especially in lung adenocarcinomas.

bioRxiv · May 29, 2026 · PreprintCancer Biology

Overcoming Cisplatin Resistance in 3D Oral Squamous Cell Carcinoma Models via Nanoparticle-Mediated Pt(IV) Drug Delivery.

Ana Belén Griso-Acevedo, Francisco Navas, Natalia L. Calvo, Victoria Morales, Beatriz Castelo, Javier Gonzalez, María José Morán Soto, Raúl Sanz, José Luis Cebrián-Carretero, Rafael A. García‐Muñoz, Ana Sastre-Perona

This study evaluates Pt(IV)-based prodrug delivery via mesoporous silica nanoparticles in 3D oral squamous cell carcinoma models, showing improved cytotoxicity and apoptotic effects compared to cisplatin.

bioRxiv · Feb 23, 2026 · PreprintCancer Biology