Author

Manoor Prakash Hande

National University of SingaporeORCID 0000-0002-4511-6256Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Gavin Yong-Quan Ng· 2 shared Aik Kia KhawiD· 1 shared Aloysius Poh Leong Ting· 1 shared Anisha K. HundaliD· 1 shared Anne HakemiD· 1 shared Asfa Alli ShaikiD· 1 shared Brendan Craig DicksoniD· 1 shared Brian Keith KennedyiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

Gavin Yong-Quan Ng

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3 papers

Recent·Most cited

Cell BiologyMutation Research/Genetic Toxicology and Environmental MutagenesisPeer-reviewedSep 10, 2025

Role of Cockayne Syndrome B (CSB) Protein in Genome Maintenance in Human Cells under Oxidative Stress

Grace Kah Mun Low, Gavin Yong-Quan Ng, Dimphy Zeegers…·Manoor Prakash Hande

This study investigates the role of CSB protein in genome maintenance under oxidative stress, finding that CSB-deficient cells show resistance to acute stress but accelerated senescence under chronic conditions.

1 citation

humanDNA methylation

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Molecular BiologyNature Structural & Molecular BiologyPeer-reviewedApr 17, 2024

DNA double-strand break-capturing nuclear envelope tubules drive DNA repair

Mitra Shokrollahi, Mia Stanić, Anisha K. Hundal…·Karim Mekhail

The paper shows that DNA double-strand breaks are repaired by nuclear envelope tubules formed through cytoplasmic microtubule interactions, enhancing repair accuracy and cancer therapy efficacy.

70 citationstop 1%

humanDNA methylation

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NeurosciencebioRxivPreprintMar 22, 2020

Integrative Epigenomic and Transcriptomic Analysis Reveals Robust Metabolic Switching in the Brain During Intermittent Fasting

Gavin Yong-Quan Ng, Dominic Paul Lee Kok Sheng, Sung Wook Kang…·Thiruma Valavan Arumugam

This study shows intermittent fasting modulates H3K9me3 epigenetic marks and transcriptomic changes in mouse cerebellum, with lasting effects after refeeding.

1 citation

mouseChIP-seq

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