The paper identifies key components for building a baseline evolutionary model of Plasmodium falciparum to better understand genomic variation and drug resistance.

bioRxiv · Jul 21, 2026 · PreprintEvolutionary Biology

Population genomics of Plasmodium ovale species in sub-Saharan Africa

Kelly Carey-Ewend, Zachary R. Popkin-Hall, Alfred Simkin, Meredith Muller, Christopher M. Hennelly, Wenqiao He, Kara A. Moser, Claudia Gaither, Karamoko Niaré, Farhang F. Aghakhanian, Sindew Mekasha Feleke, Bokretsion Gidey Brhane, Fernandine Phanzu, Kashamuka Mwandagalirwa, Özkan Aydemir, , Jessica T. Lin

This study performs population genomic analysis of Plasmodium ovale species in sub-Saharan Africa, finding differences in nucleotide diversity and signatures of selection between the two species.

bioRxiv · Apr 10, 2024 · PreprintGenomics

A novel CRISPR-based malaria diagnostic capable of Plasmodium detection, speciation, and drug-resistance genotyping

Clark H. Cunningham, Christopher M. Hennelly, Jessica T. Lin, Ratawan Ubalee, Ross M. Boyce, Edgar Mugema Mulogo, Nicholas J. Hathaway, Kyaw L. Thwai, Fernandine Phanzu, Albert Ntumba Kalonji, Kashamuka Mwandagalirwa, Antoinette Tshefu, SR Meshnick, JJ Juliano, Jonathan B. Parr

Novel malaria SHERLOCK assays enabled robust detection, speciation, and genotyping of Plasmodium spp. in diverse samples collected in Africa and Asia.

EBioMedicine · Jun 1, 2021Peer-reviewedMolecular Biology