Author

Anna J. Cruz

Broad InstituteORCID 0000-0002-4517-179XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Alejandro CollinsiD· 1 shared B BernsteiniD· 1 shared Charles B. EpsteiniD· 1 shared Daniel F. VoytasiD· 1 shared Eugenio MatteiiD· 1 shared Fadi J. NajmiD· 1 shared James C. ChamnessiD· 1 shared Jason Daniel BuenrostroiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Alejandro CollinsORCID

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2 papers

Recent·Most cited

Plant BiologyPLANT PHYSIOLOGYPeer-reviewedFeb 21, 2025

Viral delivery of recombinases to activate heritable genetic switches in plants

James C. Chamness, Jon P. Cody, Anna J. Cruz, Daniel F. Voytas

This study demonstrates that viral vectors can deliver and stably express recombinases in plants, enabling heritable genetic modifications and lineage tracing.

12 citations

plant (other)experimental assay

𝕏 PostBluesky

Molecular BiologyNature CommunicationsPeer-reviewedFeb 4, 2025

Multi-locus CRISPRi targeting with a single truncated guide RNA

Molly M. Moore, Siddarth Wekhande, Robbyn Issner…·Fadi J. Najm

This paper develops a CRISPRi approach using truncated guides to screen multiple transcription factor binding sites, showing they can disrupt enhancer activity and repress transcription factor binding.

6 citations

humanCRISPR screen

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