Author

Molly M. Moore

Broad InstituteORCID 0000-0002-7833-0769Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Alejandro CollinsiD· 2 shared B BernsteiniD· 2 shared Fadi J. NajmiD· 2 shared Nauman M. JavediD· 2 shared Anna J. CruziD· 1 shared Charles B. EpsteiniD· 1 shared Eugenio MatteiiD· 1 shared Gary SuniD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Alejandro CollinsORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Multi-locus CRISPRi targeting with a single truncated guide RNA

Molly M. Moore, Siddarth Wekhande, Robbyn Issner, Alejandro Collins, Anna J. Cruz, Yanjing V. Liu, Nauman M. Javed, Salvador Casaní-Galdón, Jason Daniel Buenrostro, Charles B. Epstein, Eugenio Mattei, John G. Doench, B Bernstein, Noam Shoresh F, Fadi J. Najm

This paper develops a CRISPRi approach using truncated guides to screen multiple transcription factor binding sites, showing they can disrupt enhancer activity and repress transcription factor binding.

Nature Communications · Feb 4, 2025Peer-reviewedMolecular Biology

Integrative dissection of gene regulatory elements at base resolution

Zeyu Chen, Nauman M. Javed, Molly M. Moore, Jingyi Wu, Gary Sun, Michael E. Vinyard, Alejandro Collins, Luca Pinello, Fadi J. Najm, B Bernstein

The paper identifies critical base-resolution regulatory elements in immune gene expression using base editing and deep learning.

Cell Genomics · Apr 28, 2023Peer-reviewedMolecular Biology