Author

Bjørn Holst

Bioneer (Denmark)ORCID 0000-0002-4517-6881Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1

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Benjamin SchmidiD· 1 shared Bharti NawalpuriiD· 1 shared Gunnar K. GourasiD· 1 shared Kristine FreudeiD· 1 shared Ravi Sondekoppa MuddashettyiD· 1 shared Sabine C KoningsiD· 1 shared Sarayu RamakrishnaiD· 1 shared Sumita Chakraborty· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperNeuroscience

Benjamin SchmidORCID

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1 paper

Recent·Most cited

NeuroscienceJournal of NeurosciencePeer-reviewedSep 2, 2021

APOE4 affects basal and NMDAR mediated protein synthesis in neurons by perturbing calcium homeostasis

Sarayu Ramakrishna, Vishwaja Jhaveri, Sabine C Konings…·Ravi Sondekoppa Muddashetty

This study shows APOE4 disrupts calcium homeostasis in neurons, leading to sustained translation inhibition and impaired NMDAR signaling, while APOE3 causes a transient calcium response with recovery.

33 citations

experimental assay

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