Author

Sumita Chakraborty

Institute for Stem Cell Biology and Regenerative Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Ravi Sondekoppa MuddashettyiD· 2 shared Aditi BhattacharyaiD· 1 shared Benjamin SchmidiD· 1 shared Bharti NawalpuriiD· 1 shared Bjørn HolstiD· 1 shared Gunnar K. GourasiD· 1 shared Kristine FreudeiD· 1 shared Sabine C KoningsiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Ravi Sondekoppa MuddashettyORCID

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2 papers

Recent·Most cited

APOE4 affects basal and NMDAR mediated protein synthesis in neurons by perturbing calcium homeostasis

Sarayu Ramakrishna, Vishwaja Jhaveri, Sabine C Konings, Bharti Nawalpuri, Sumita Chakraborty, Bjørn Holst, Benjamin Schmid, Gunnar K. Gouras, Kristine Freude, Ravi Sondekoppa Muddashetty

This study shows APOE4 disrupts calcium homeostasis in neurons, leading to sustained translation inhibition and impaired NMDAR signaling, while APOE3 causes a transient calcium response with recovery.

Journal of Neuroscience · Sep 2, 2021Peer-reviewedNeuroscience

Distinct Regulation of Bioenergetics and Translation by Gp I mGluR and NMDAR

Sudhriti Ghosh Dastidar, Shreya Das Sharma, Sumita Chakraborty, Sumantra Chattarji, Aditi Bhattacharya, Ravi Sondekoppa Muddashetty

The paper shows that mGluR and NMDAR regulate protein synthesis and ATP consumption in cortical neurons through distinct kinetics and AMPK-eEF2 signaling.

EMBO Reports · Apr 29, 2020Peer-reviewedNeuroscience