Yibo Zhao

This study shows that LRRK2 regulates synaptic function by modulating actin cytoskeletal dynamics through BDNF signaling in neurons.

This study shows that evolutionary divergence in LRRK2 interaction domains leads to species-specific protein interaction networks in humans and mice.

The paper compares inflammatory markers in sporadic and LRRK2-associated Parkinson's using transcriptomics and proteomics to identify molecular differences and a protein cluster linked to tau pathology.

This study identifies PAK6 as a modifier of LRRK2 mutations, showing it rescues ciliogenesis defects in G2019S but not R1441C mutations.

The paper compares transcriptomic changes in LRRK2 protein interactors between sporadic and LRRK2 Parkinson's Disease to identify molecular differences.

The paper constructs tissue-specific LRRK2 interactomes and identifies a functional cluster within the striatum, highlighting distinct expression patterns and interactions in brain regions.