Author

Willie J.C. Geerts

ORCID 0000-0002-4530-7458Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

Aikaterini Konstantoulea· 1 shared Friedrich G. Förster· 1 shared Laura S. van Bezouwen· 1 shared Luca FerrariiD· 1 shared Marloes van Wezel· 1 shared Renate Kos· 1 shared Stefan G.D. RüdigeriD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Aikaterini Konstantoulea

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1 paper

Recent·Most cited

Human chaperones untangle fibrils of the Alzheimer protein Tau

Luca Ferrari, Willie J.C. Geerts, Marloes van Wezel, Renate Kos, Aikaterini Konstantoulea, Laura S. van Bezouwen, Friedrich G. Förster, Stefan G.D. Rüdiger

This study shows human Hsp70 chaperones can dissolve Tau fibrils, while bacterial Hsp70 systems cannot, suggesting evolutionary adaptation for fibril disaggregation and potential therapeutic applications for Alzheimer's.

bioRxiv · Sep 26, 2018 · PreprintBiochemistry