Single-cell analysis of human lung epithelia reveals concomitant expression of the SARS-CoV-2 receptor ACE2 with multiple virus receptors and scavengers in alveolar type II cells
Guangchun Han, Ansam F. Sinjab, Warapen Treekitkarnmongkol, Patrick M. Brennan, Kieko Hara, Kyle Chang, Elena Bogatenkova, Beatriz Sánchez‐Espiridión, Carmen Behrens, Boning Gao, Luc Girard, Jianjun Zhang, Boris Sepesi, Tina Cascone, Lauren A. Byers, , Humam N. Kadara
The paper analyzes single-cell RNA-seq data to identify ACE2 expression patterns in human lung epithelial cells, finding high ACE2 expression in alveolar type II cells and co-expression with pathogen receptors.
bioRxiv · Apr 16, 2020 · PreprintGenomics