Author

Nahye Kim

Harvard UniversityORCID 0000-0002-4539-6382Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Research Focus:protein design· 1 Assay:proteomics· 1

Frequent Co-Authors

Benjamin P. KleinstiveriD· 2 shared Rachel A. SilversteiniD· 2 shared Aadyot Bhatnagar· 1 shared Alexander J. MeeskeiD· 1 shared Ali MadaniiD· 1 shared Andrey Novichkov· 1 shared C.K. Fong· 1 shared Casey A. MaguireiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBioengineering

Benjamin P. KleinstiverORCID

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2 papers

Recent·Most cited

BioengineeringNature Biomedical EngineeringPeer-reviewedSep 11, 2025

In vivo Treatment of a Severe Vascular Disease via a Bespoke CRISPR-Cas9 Base Editor

Christiano R. R. Alves, Sabyasachi Das, Vijai Krishnan…·Patricia Leonor Musolino

This paper develops a customized CRISPR-Cas9 base editor to correct the ACTA2 R179H mutation in a mouse model of MSMDS, improving survival and rescuing vascular and neurological phenotypes.

13 citations

mousegenetic perturbation / CRISPR

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintJan 6, 2025

Engineering of CRISPR-Cas PAM recognition using deep learning of vast evolutionary data

Stephen Nayfach, Aadyot Bhatnagar, Andrey Novichkov…·Ali Madani

This paper introduces Protein2PAM, a deep learning model that predicts CRISPR-Cas PAM specificity from protein sequences, enabling the design of Cas variants with tailored PAM recognition.

5 citations

proteomicsdeep learning

𝕏 PostBluesky