Author

C.K. Fong

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1

Frequent Co-Authors

David Y. ChungiD· 2 shared Mark Evan LindsayiD· 2 shared Patricia Leonor MusolinoiD· 2 shared Pazhanichamy KalailingamiD· 2 shared Takahiko ImaiiD· 2 shared Vijai KrishnaniD· 2 shared Aarushi Gandhi· 1 shared Angelyna Siv· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersPhysiology

David Y. ChungORCID

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2 papers

Recent·Most cited

Smooth Muscle Dysfunction Drives Cerebrovascular Reserve Failure and End-Organ Brain Injury

Takahiko Imai, Vijai Krishnan, James Han Lai, Elyssa Alber, Lydia Hawley, Aarushi Gandhi, Pazhanichamy Kalailingam, Joanna Yang, Diana Tambala, David Hike, Xiaoqing Alice Zhou, C.K. Fong, Benjamin Ondeck, Emily Da Cruz, Xiaochen Liu, , David Y. Chung

This study shows that smooth muscle dysfunction caused by ACTA2 mutations leads to cerebrovascular reserve failure, increasing brain vulnerability to hypoperfusion and injury.

bioRxiv · Jan 26, 2026 · PreprintPhysiology

In vivo Treatment of a Severe Vascular Disease via a Bespoke CRISPR-Cas9 Base Editor

Christiano R. R. Alves, Sabyasachi Das, Vijai Krishnan, Leillani L. Ha, Lauren R. Fox, Hannah E. Stutzman, Claire E. Shamber, Pazhanichamy Kalailingam, Siobhan McCarthy, Christian Lacks Lino Cardenas, C.K. Fong, Takahiko Imai, Sunayana Mitra, Shuqi Yun, Rachael K. Wood, , Patricia Leonor Musolino

This paper develops a customized CRISPR-Cas9 base editor to correct the ACTA2 R179H mutation in a mouse model of MSMDS, improving survival and rescuing vascular and neurological phenotypes.

Nature Biomedical Engineering · Sep 11, 2025Peer-reviewedBioengineering