Author

Vijai Krishnan

Harvard UniversityORCID 0000-0001-5979-1255Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:imaging· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:rat· 1

Frequent Co-Authors

C.K. Fong· 2 shared David Y. ChungiD· 2 shared Mark Evan LindsayiD· 2 shared Patricia Leonor MusolinoiD· 2 shared Pazhanichamy KalailingamiD· 2 shared Takahiko ImaiiD· 2 shared Aarushi Gandhi· 1 shared Alan P. KoretskyiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPhysiology

C.K. Fong

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PhysiologybioRxivPreprintJan 26, 2026

Smooth Muscle Dysfunction Drives Cerebrovascular Reserve Failure and End-Organ Brain Injury

Takahiko Imai, Vijai Krishnan, James Han Lai…·David Y. Chung

This study shows that smooth muscle dysfunction caused by ACTA2 mutations leads to cerebrovascular reserve failure, increasing brain vulnerability to hypoperfusion and injury.

DOI 10.64898/2026.01.26.701890

mouseimaging

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BioengineeringNature Biomedical EngineeringPeer-reviewedSep 11, 2025

In vivo Treatment of a Severe Vascular Disease via a Bespoke CRISPR-Cas9 Base Editor

Christiano R. R. Alves, Sabyasachi Das, Vijai Krishnan…·Patricia Leonor Musolino

This paper develops a customized CRISPR-Cas9 base editor to correct the ACTA2 R179H mutation in a mouse model of MSMDS, improving survival and rescuing vascular and neurological phenotypes.

13 citations

mousegenetic perturbation / CRISPR

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NeuroscienceJournal of Neuroscience MethodsPeer-reviewedApr 23, 2020

High-resolution MEMRI characterizes laminar specific ascending and descending spinal cord pathways in rats

Vijai Krishnan, Jiadi Xu, Albert German Mendoza…·Galit Pelled

This study uses MEMRI to visualize laminar-specific spinal cord pathways in rats, showing T1 signal enhancement in specific laminae after MnCl2 administration.

3 citations

ratimaging

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