NeurosciencebioRxivPreprint
Highly conserved brain vascular receptor ALPL mediates transport of engineered viral vectors across the blood-brain barrier
Tyler Chistopher Moyer, Brett A. Hoffman, Weitong Chen…·Mathieu E. Nonnenmacher
This study identifies VCAP-102, an AAV9 variant with enhanced brain delivery across species, mediated by ALPL receptor interaction.
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