Author

Andrzej Kazimierz Bednarek

Medical University of LodzORCID 0000-0002-4570-4154Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrianna Stępień· 1 shared Agnieszka RobaszkiewicziD· 1 shared Karolina GronkowskaiD· 1 shared Maciej BorowieciD· 1 shared Magdalena StrachowskaiD· 1 shared Sylwia MichlewskaiD· 1 shared Tomasz PłoszajiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Adrianna Stępień

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1 paper

Recent·Most cited

BRG1 targeting overcomes ABCC-based multidrug resistance induced by paclitaxel

Karolina Gronkowska, Sylwia Michlewska, Tomasz Płoszaj, Magdalena Strachowska, Adrianna Stępień, Maciej Borowiec, Andrzej Kazimierz Bednarek, Agnieszka Robaszkiewicz

This study shows that BRG1-based SWI/SNF complex promotes ABCC gene transcription, contributing to paclitaxel resistance, and that targeting BRG1 can overcome this resistance.

Journal of Pharmacology and Experimental Therapeutics · Nov 10, 2025Peer-reviewedCancer Biology