Agnieszka Robaszkiewicz

The paper identifies the Txn-Txnrd1 system as critical for redox homeostasis in polyaneuploid giant cancer cells, linking it to therapy resistance and poor patient outcomes.

This paper optimizes lipid anchor engineering to enhance siRNA delivery efficiency using R9-Chol-functionalized liposomes, achieving effective EGFR gene silencing in triple-negative breast cancer cells.

This study shows that BRG1-based SWI/SNF complex promotes ABCC gene transcription, contributing to paclitaxel resistance, and that targeting BRG1 can overcome this resistance.

This study shows p53 suppresses E2F1-driven genes by maintaining KDM5B at promoters, inhibiting p300-mediated transcription in response to cisplatin.