Author

Jonathan G. Boucher

Institute for Research in Immunology and CancerORCID 0000-0002-4586-3059Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Philippe P. RouxiD· 2 shared Alexandra MoisandiD· 1 shared Assia Chaïbi· 1 shared Atika Zouine· 1 shared Audrey Theodoly-Lannes· 1 shared Baptiste LamarthéeiD· 1 shared Bernard BonnotteiD· 1 shared Céline BlayeiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Philippe P. RouxORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintFeb 21, 2025

Immunosuppressive myeloid cells induce mesenchymal-like breast cancer stem cells by a mechanism involving membrane-bound TGF-β1.

Thomas Boyer, Céline Blaye, Domitille Chalopin…·Nicolas Larmonier

DOI 10.1101/2025.02.21.639264

humanbulk RNA-seq

Molecular BiologyCell Death DiscoveryPeer-reviewedDec 16, 2023

The CDK12 inhibitor SR-4835 functions as a molecular glue that promotes cyclin K degradation in melanoma

Thibault Houlès, Jonathan G. Boucher, Geneviève Lavoie…·Philippe P. Roux

This study identifies SR-4835 as a CDK12 inhibitor that promotes cyclin K degradation via the proteasome by recruiting the CDK12-cyclin K complex to the CUL4-RBX1-DDB1 ubiquitin ligase complex.

49 citationstop 3%

humanexperimental assay