NeuroscienceActa Neuropathologica CommunicationsPeer-reviewed
Feeding Schedule And Proteolysis Regulate Autophagic Clearance Of Mutant Huntingtin
Dagmar E. Ehrnhoefer, Dale D. O. Martin, Mandi E. Schmidt…·Michael R. Hayden
This study shows that scheduled feeding and prevention of caspase-6 cleavage enhance autophagic clearance of mutant huntingtin in HD models and patients.
82 citations