Author

Fern A Hughes

MRC London Institute of Medical SciencesORCID 0000-0002-4599-5027Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Organism:bacteria (other)· 1 Approach:Bayesian inference· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Alexis R. BarriD· 2 shared Philipp ThomasiD· 2 shared Louise FetsiD· 1 shared Maria SecrieriD· 1 shared Paula Ortega-PrietoiD· 1 shared S. Desai· 1 shared S. J. Cutty· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

Alexis R. BarrORCID

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2 papers

Recent·Most cited

Pro-survival roles for p21(Cip1/Waf1) in Non-Small Cell Lung Cancer

S. J. Cutty, Fern A Hughes, Paula Ortega-Prieto, S. Desai, Philipp Thomas, Louise Fets, Maria Secrier, Alexis R. Barr

This study shows that p21Cip1/Waf1 promotes survival and relapse in TP53 wild-type NSCLC by enabling quiescence and protecting cells from chemotherapy.

British Journal of Cancer · Dec 20, 2024Peer-reviewedCancer Biology

Patterns of interdivision time correlations reveal hidden cell cycle factors

Fern A Hughes, Alexis R. Barr, Philipp Thomas

The paper identifies three interdivision time correlation patterns in cell cycle timing using Bayesian inference on single-cell datasets, revealing hidden rhythmicity and disease-related differences.

eLife · Nov 15, 2022Peer-reviewedSystems Biology