Patricia Rockwell

This study identifies terazosin as a drug that reverses AD-related molecular signatures and preserves noradrenergic circuits in a sex-dependent manner in a rat model of Alzheimer's disease.

This paper identifies agomelatine as a disease-modifying candidate for Alzheimer's disease, showing sex-specific neuroprotection and reduced pathology in both rat and human models.

The paper investigates BT-11's effects on AD-like pathology in rats, finding improvements in cognition and reduction in Aβ plaques and neuronal loss.

This study shows RG2833, an HDAC1/3 inhibitor, improves spatial memory in female Alzheimer's model rats but not males, with no effect on amyloid beta or microgliosis.

This paper evaluates the combined treatment of diazoxide and dibenzoylmethane in Alzheimer's transgenic rats, showing improved spatial memory, reduced pathology, and upregulated protective genes.

The paper investigates the PGD2 pathway in a transgenic rat model of Alzheimer's disease and shows that timapiprant, a DP2 antagonist, mitigates AD pathology.

The paper compares spatial learning in male and female TgF344-AD rats, finding females perform better despite higher amyloid plaques and microgliosis.