M2 Cortex-Dorsolateral striatum stimulation reverses motor symptoms and synaptic deficits in Huntington's Disease
Sara Fernández‐García, Sara Conde-Berriozabal, Esther García-García, Clara Gort‐Paniello, David Bernal‐Casas, Gerardo Garcia-Díaz Barriga, Xavier López-Gil, Emma Muñoz‐Moreno, Guadalupe Sòria, Leticia Campa, Francesc Artigas, Manuel José Rodríguez, Jordi Alberch, Mercè Masana
This study shows that optogenetic stimulation of fronto-striatal pathways in HD mice improves motor symptoms and synaptic plasticity.
eLife · Oct 5, 2020Peer-reviewedNeuroscience