Gerardo Garcia-Díaz Barriga

The paper identifies a disease-associated microglial state in AD using transcriptomics and shows a compound can reverse it.

The paper investigates how human and bacterial amyloids affect enteric glia and smooth muscle cells, finding they trigger a pro-inflammatory response and DNA damage.

This study shows that optogenetic stimulation of fronto-striatal pathways in HD mice improves motor symptoms and synaptic plasticity.

The paper develops a proximity ligation-based method to improve synapse quantification in neuronal cultures by reducing false positives and increasing sensitivity.

The paper develops a microscopy-based pipeline to quantify neuronal network connectivity and identifies compounds that enhance connectivity and provide neuroprotection.