Author

Paul B. Savage

Waters (United States)ORCID 0000-0002-4642-6109Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell signaling & trafficking· 1 Approach:mechanistic / dynamical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Alexandre F. Gomes· 1 shared Amita Rani SahooiD· 1 shared Lindsay J. MorrisoniD· 1 shared Matthias BuckiD· 1 shared Nisha BhattaraiiD· 1 shared

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2025-2025 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBiophysics

Alexandre F. Gomes

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintMar 13, 2025

Computation model predicts Rho GTPase function with the Plexin Transmembrane receptor GAP activity on Rap1b via dynamic allosteric changes

Nisha Bhattarai, Lindsay J. Morrison, Alexandre F. Gomes…·Matthias Buck

The paper uses molecular dynamics simulations to analyze conformational changes in Plexin-B1 bound to Rap1b, Rnd1, and Rac1, revealing differences in dynamics and interactions.

DOI 10.1101/2025.03.13.643120

structural biologymechanistic / dynamical model

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