Vincent Rubinetti

Scalable data harmonization for single-cell image-based profiling with CytoTable

The paper introduces CytoTable, a software package that harmonizes single-cell image-based profiling data from different tools, enabling reproducible and scalable data integration.

STRchive: a dynamic resource detailing population-level and locus-specific insights at tandem repeat disease loci

STRchive provides a dynamic resource for interpreting TR variants at disease loci, showing most TR diseases affect children and pathogenic genotypes exist in gnomAD without known disease prevalence.

Hetnet connectivity search provides rapid insights into how two biomedical entities are related

The paper introduces hetnet connectivity search to find meaningful relationships between biomedical entities in heterogeneous networks without requiring supervised training data.

MolEvolvR: A web-app for characterizing proteins using molecular evolution and phylogeny

MolEvolvR provides a web-app for analyzing protein evolution through phylogenetic context, offering tools to explore conserved domains, lineage-specific variants, and domain architectures.

Linguistic Analysis of the bioRxiv Preprint Landscape

The paper analyzes linguistic features of bioRxiv preprints compared to published biomedical texts and develops tools to link preprints to peer-reviewed articles and journals.

Sequential compression of gene expression across dimensionalities and methods reveals no single best method or dimensionality

The paper evaluates multiple compression methods and dimensionalities on gene expression data, finding no single best approach but showing benefits from ensemble methods across different dimensions.