An unbiased cell-culture selection yields DNA aptamers as novel senescent cell-specific reagents
Keenan S. Pearson, Sarah K. Jachim, Caroline Lloyd Doherty, Brandon A. Wilbanks, Luis I. Prieto, Maria B. Dugan, Darren J. Baker, Nathan K. LeBrasseur, Louis James Maher III
This study uses unbiased cell culture selections to identify DNA aptamers specific to senescent cells, demonstrating their utility as reagents for detecting senescent cells in vitro and in tissues.
Aging Cell · Sep 19, 2025Peer-reviewedBiochemistry