Nathan K. LeBrasseur

Suppression of early pro-inflammatory senescent signature post-radiotherapy mitigates chronic bone damage

This study shows that early suppression of the pro-inflammatory senescent secretome (SASP) with ruxolitinib reduces chronic bone damage after radiotherapy.

Comprehensive healthspan assessments and influence of sex as a biological variable in aging rats

This study presents a longitudinal assessment of age-related changes in Brown-Norway rat physiology and histopathology at 6, 17, and 27 months of age to provide healthspan parameters for aging research.

An unbiased cell-culture selection yields DNA aptamers as novel senescent cell-specific reagents

This study uses unbiased cell culture selections to identify DNA aptamers specific to senescent cells, demonstrating their utility as reagents for detecting senescent cells in vitro and in tissues.

Single-cell Mayo Map (scMayoMap): an easy-to-use tool for cell type annotation in single-cell RNA-sequencing data analysis

scMayoMap provides a user-friendly tool for accurate cell type annotation in scRNA-seq data, outperforming existing methods across multiple datasets.