Author

Zhifei Luo

University of California San DiegoORCID 0000-0002-4691-8074Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:spatial domain detection· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

John Lalith Charles RichardiD· 2 shared Riccardo CalandrelliiD· 2 shared Sheng ZhongiD· 2 shared Tri C. NguyeniD· 2 shared Xingzhao WeniD· 2 shared Bing ReniD· 1 shared Chien-Ju CheniD· 1 shared Jian MaiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

John Lalith Charles RichardORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintJun 30, 2026

A Simple, Cost-Effective, High-Throughput Method for Measuring Chromatin Accessibility and Gene Expression in Single Nuclei

Zhifei Luo, William James Greenleaf

The paper introduces and benchmarks two droplet-based single-nucleus assays for chromatin accessibility and gene expression, showing they are cost-effective and produce high-quality data.

DOI 10.64898/2026.06.29.735326

mousescATAC-seq

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GenomicsNature CommunicationsPeer-reviewedOct 16, 2023

Genome-wide analysis of the interplay between chromatin-associated RNA and 3D genome organization in human cells

Riccardo Calandrelli, Xingzhao Wen, John Lalith Charles Richard…·Sheng Zhong

This study investigates how chromatin-associated RNA interacts with 3D genome organization in human cells, revealing a feedback loop between RNA distribution and chromatin structure.

57 citationstop 3%

humanChIP-seq

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GenomicsbioRxivPreprintJun 28, 2023

Single-cell multiplex chromatin and RNA interactions in aging human brain

Xingzhao Wen, Zhifei Luo, Wenxin Zhao…·Sheng Zhong

The paper introduces MUSIC, a technique to profile chromatin interactions, gene expression, and RNA-chromatin associations in single cells, revealing age-related changes and disease associations in human brain samples.

3 citations

humanChIP-seq

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