Author

Jeffrey Zheng

Duke UniversityORCID 0000-0002-4691-9317Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Adam R. RensloiD· 1 shared Alan AshworthiD· 1 shared Brian K. ShoichetiD· 1 shared Dewey Granville McCaffertyiD· 1 shared Eric R. HantziD· 1 shared G.J. CorreyiD· 1 shared James S. FraseriD· 1 shared Julia RosecransiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPharmacology & Toxicology

Adam R. RensloORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyJournal of Medicinal ChemistryPeer-reviewedDec 17, 2025

Discovery of AVI-6451, a Potent and Selective Inhibitor of the SARS-CoV-2 ADP-Ribosylhydrolase Mac1 with Oral Efficacy in vivo

Priyadarshini Jaishankar, G.J. Correy, Yusuke Matsui…·Adam R. Renslo

This paper identifies AVI-6451, an orally bioavailable inhibitor of SARS-CoV-2 Mac1 with once-daily efficacy in a mouse model.

6 citationstop 4%

mouseexperimental assay

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BioinformaticsbioRxivPreprintMay 22, 2020

Targeted Genome Mining Discovery of the Ramoplanin Congener Chersinamycin from the Dynemicin-Producer Micromonospora chersina DSM 44154.

Kelsey T. Morgan, Jeffrey Zheng, Dewey Granville McCafferty

The paper identifies a new ramoplanin-like biosynthetic gene cluster in Micromonospora chersina and validates its function through CRISPR-Cas9 gene editing, leading to the discovery of the antibiotic chersinamycin.

DOI 10.1101/2020.05.22.111625

experimental assay

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