Cell BiologybioRxiv
Ubiquitination-activated TAB-TAK1-IKK-NF-kB axis modulates gene expression for cell survival in the lysosomal damage response
Akinori Endo, Chikage Takahashi, Naoko Ishibashi…·Yukiko Yoshida
The paper identifies the TAB-TAK1-IKK-NF-κB axis as a ubiquitin-regulated pathway activated by lysosomal damage, promoting cell survival through anti-apoptotic and intercellular signaling genes.
6 citations