Yuval Silberman

An altered cell-specific subcellular distribution of translesion synthesis DNA polymerase kappa (POLK) in aging neurons

This study shows that DNA polymerase kappa (POLK) shifts from the nucleus to the cytoplasm in aging neurons, correlating with increased DNA damage and stress granule accumulation.

The vagus nerve is critical for regulation of hypothalamic-pituitary-adrenal axis responses to acute stress

This study investigates the role of the vagus nerve in regulating HPA axis responses to acute stress using rat models.

Ketamine blocks morphine-induced conditioned place preference and anxiety-like behaviors in mice.

This study shows that ketamine blocks morphine-induced conditioned place preference and anxiety-like behaviors in mice, suggesting it may interfere with memory of morphine-context associations rather than just alleviating negative affective states.

Chronic intermittent ethanol and acute stress similarly modulate BNST CRF neuron activity via noradrenergic signaling

This study shows that chronic intermittent ethanol and acute stress similarly affect BNST CRF neuron activity through noradrenergic signaling, disrupting beta-adrenergic receptor balance.