Author

Mofida Abdelmageed

Pennsylvania State UniversityORCID 0000-0001-9507-4296Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Anirban PauliD· 2 shared Anirban PauliD· 1 shared Aron E. LukacheriD· 1 shared Arrienne B. ButiciD· 1 shared Arvin Koshboresh· 1 shared ChaeMin KimiD· 1 shared Deniz ParmaksiziD· 1 shared Elia AfanasieviD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Anirban PaulORCID

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Author profile →

3 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 14, 2026

Neuronal and vascular genome-maintenance states organize opposing multicellular architectures in the aging brain

Arvin Koshboresh, Vijay Laxmi Roy, Mofida Abdelmageed…·Anirban Paul

The paper maps DNA damage response states in aging mouse brains, revealing opposing neuronal and vascular spatial patterns linked to genome maintenance.

DOI 10.64898/2026.09.07.749801

mousescRNA-seq

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ImmunologyDOAJ (DOAJ: Directory of Open Access Journals)Peer-reviewedAug 17, 2026

PD-1 regulates CD4+ T cell-mediated CD8+ T cell responses in the brain to balance viral control and neuroinflammation

Arrienne B. Butic, Elia Afanasiev, Samantha A. Spencer…·Aron E. Lukacher

This study shows PD-1 in CD4+ T cells balances antiviral defense and neuroinflammation during polyomavirus CNS infection by modulating CD8+ T cell responses.

DOI 10.1038/s41467-026-76762-3

mousescRNA-seq

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NeurosciencebioRxivPreprintSep 27, 2023

An altered cell-specific subcellular distribution of translesion synthesis DNA polymerase kappa (POLK) in aging neurons

Mofida Abdelmageed, Premkumar Palanisamy, Victoria L. Vernail…·Anirban Paul

This study shows that DNA polymerase kappa (POLK) shifts from the nucleus to the cytoplasm in aging neurons, correlating with increased DNA damage and stress granule accumulation.

DOI 10.1101/2023.09.27.559771

humanexperimental assay

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