Hexa-acylated lipopolysaccharides from the gut microbiota enhance cancer immunotherapy responses
Puspendu Sardar, Benjamin S. Beresford-Jones, Wangmingyu Xia, Omar Shabana, Satoshi Suyama, Ruben J. Jesus Faustino Ramos, Amelia T. Soderholm, Panagiotis Tourlomousis, Paula Kuo, Alexander C. Evans, Charlotte J. Imianowski, Alberto G. Conti, Alexander J. Wesolowski, Natalie M. Baker, Emily A. L. McCord, , Virginia Ahn Pedicord
The paper identifies hexa-acylated lipopolysaccharides from the gut microbiome as a biomarker and enhancer of anti-PD-1 immunotherapy responses in melanoma patients.
Nature Microbiology · Feb 10, 2025Peer-reviewedMicrobiology