Sorcha Hamilton

This study shows ketamine reduces habenula activity during aversive learning in humans, supporting preclinical findings on its antidepressant mechanisms.

Across 15 cohorts (birth to 24 years), 20 epigenetic clocks and eight brain age models predicted chronological age modestly, stabilizing by middle childhood; their age residuals were weakly associated.

The paper shows that social affiliation rates depend on environmental features like opportunity density and success frequency, with neural correlates in subcortical circuits and links to personality traits.

The paper identifies a subcortical circuit involved in switching between threat vigilance and reward foraging in humans using fMRI.