Author

Catherine J. Wedderburn

University of Cape TownORCID 0000-0002-4887-1644Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Assay:imaging· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Dan Joseph SteiniD· 4 shared Heather Joy ZariD· 4 shared Kirsten Ann DonaldiD· 4 shared Petrus J.W. NaudéiD· 3 shared Tusekile Sarah KangwaiD· 3 shared Cesc Bertran-CoboiD· 2 shared Frances C. RobertsoniD· 2 shared J. S. AnnandaleiD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersNeuroscience

Dan Joseph SteinORCID

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Author profile →

4 papers

Recent·Most cited

Epigenetic and brain age across development: Performance and associations in the MIND consortium

Marlene Staginnus, Vilte Baltramonaityte, Isabel K. Schuurmans, Sarina Abrishamcar, Martin Bauer, Sintia Iole Belangero, Elisabeth B. Binder, Rodrigo A. Bressan, Sybil Alexandra Burt, Claudia Buß, Shi Yu Chan, Valentine Chirokoff, Shaunna Clark, H. Valerie Curran, Darina Czamara, , Esther Walton

Across 15 cohorts (birth to 24 years), 20 epigenetic clocks and eight brain age models predicted chronological age modestly, stabilizing by middle childhood; their age residuals were weakly associated.

bioRxiv · Jul 30, 2026 · PreprintNeuroscience✦ In-depth digest

Maternal and early-life longitudinal cytokine profiles in a South African birth cohort: the impact of HIV

Tusekile Sarah Kangwa, Catherine J. Wedderburn, Jenna F. Annandale, Kirsten Ann Donald, Francesca Little, Heather Joy Zar, Dan J. Stein, Petrus J.W. Naudé

This study examines cytokine profiles in HIV-exposed and unexposed children and their mothers, finding persistent immune alterations in HEU children linked to maternal HIV.

Cytokine · Jul 22, 2026Peer-reviewedImmunology

Persistent neuroimmune alterations in children who are HIV-exposed but uninfected at age 6-7 years: Associations with language development in a South African birth cohort

Cesc Bertran-Cobo, Frances C. Robertson, Simone R. Williams, Tusekile Sarah Kangwa, J. S. Annandale, Jessica E. Ringshaw, Layla E. Bradford, Nadia Hoffman, Heather Joy Zar, Dan Joseph Stein, Kirsten Ann Donald, Petrus J.W. Naudé, Catherine J. Wedderburn

This study examines neuroimmune changes in HIV-exposed uninfected children and links them to language development using a South African cohort.

bioRxiv · Mar 11, 2026 · PreprintNeuroscience

Maternal and child immune profiles are associated with neurometabolite measures of early-life neuroinflammation in children who are HIV-exposed and uninfected: a South African birth cohort

Cesc Bertran-Cobo, Frances C. Robertson, Tusekile Sarah Kangwa, Jenna Annandale, Sivenesi Subramoney, Katherine L. Narr, Shantanu H. Joshi, Nadia Hoffman, Heather Joy Zar, Dan Joseph Stein, Kirsten Ann Donald, Catherine J. Wedderburn, Petrus J.W. Naudé

The paper examines associations between maternal and child immune profiles and neurometabolite measures of neuroinflammation in HIV-exposed uninfected and HIV-unexposed children.

Wellcome Open Research · Oct 31, 2025Peer-reviewedNeuroscience