NeuroscienceScientific ReportsPeer-reviewed
α7 nicotinic acetylcholine receptor signaling modulates the inflammatory and iron homeostasis in fetal brain microglia
Marina Cortes, Mingju Cao, H. L. Liu…·Martin Gerbert Frasch
This study shows that 7nAChR agonists reverse LPS-induced pro-inflammatory microglial phenotype in fetal sheep, while antagonists enhance it, suggesting therapeutic potential for neuroinflammation.
34 citations