Author

Paolo Roberto Madeddu

Bristol Royal InfirmaryORCID 0000-0002-4718-9205Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alison M. MeynertiD· 1 shared Andrea CaporaliiD· 1 shared Andrew Howard BakeriD· 1 shared Anita C. ThomasiD· 1 shared Annabell Fricker· 1 shared Antonella Maria NogaraiD· 1 shared David W. TollerveyiD· 1 shared Elisa AvolioiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Alison M. MeynertORCID

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2 papers

Recent·Most cited

Regulation of BACH1 by hemin improves cardiac function in a mouse model of myocardial infarction

Valeria Vincenza Alvino, Rajesh Katare, Annabell Fricker, Elisa Avolio, Massimo Caputo, Paolo Roberto Madeddu, Sadie C. Slater

This study shows hemin treatment reduces BACH1 and increases HMOX1 in a mouse MI model, improving cardiac function and vascular density.

bioRxiv · Oct 3, 2023 · PreprintMolecular Biology

EZH2 interacts with MEG3 to directly regulate integrin signaling and endothelial cell function

Tatiana Dudnakova, Hywel Dunn-Davies, Antonella Maria Nogara, Julie Rodor, Anita C. Thomas, Elisa Parish, Philippe Emmanuel Gautier, Alison M. Meynert, Paolo Roberto Madeddu, Andrea Caporali, Andrew Howard Baker, David W. Tollervey, Tijana Mitić

The paper identifies EZH2's interaction with MEG3 to regulate integrin signaling and endothelial cell function through epigenetic mechanisms.

bioRxiv · May 20, 2022 · PreprintMolecular Biology