Author

Hywel Dunn-Davies

Institute of Genetics and CancerORCID 0000-0003-3975-788XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Philippe Emmanuel GautieriD· 3 shared Alain J. Kemp· 1 shared Alex von KriegsheimiD· 1 shared Alice LepelleyiD· 1 shared Alison M. MeynertiD· 1 shared Andrea CaporaliiD· 1 shared Andreas FellasiD· 1 shared Andrew Howard BakeriD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersImmunology

Philippe Emmanuel GautierORCID

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3 papers

Recent·Most cited

ImmunologyNature CommunicationsPeer-reviewedOct 8, 2026

ATRX Deficiency Drives Aberrant Type I Interferon Signalling Through cGAS-Dependent Transcriptional Dysregulation

Marie‐Thérèse El‐Daher, Eve L. White, Andreas Fellas…·Yanick Joseph Crow

This study identifies ATRX deficiency as a driver of aberrant type I interferon signaling via cGAS-dependent transcriptional dysregulation in patients with cerebral white matter disease.

2 citationstop 4%

humanDNA methylation

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Cancer BiologyDevelopmental CellPeer-reviewedAug 15, 2025

Dysproteostasis primes pancreatic epithelial state changes in KRAS-mediated oncogenesis

Carla Salomo-Coll, Marisa Di Monaco, Jocelyn Holkham…·Simon Wilkinson

This study shows that proteostatic failure in ER-phagy, driven by Kras, leads to protein aggregates that prime acinar-ductal metaplasia and pancreatic cancer.

7 citationstop 4%

mouseproteomics

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Molecular BiologybioRxivPreprintMay 20, 2022

EZH2 interacts with MEG3 to directly regulate integrin signaling and endothelial cell function

Tatiana Dudnakova, Hywel Dunn-Davies, Antonella Maria Nogara…·Tijana Mitić

The paper identifies EZH2's interaction with MEG3 to regulate integrin signaling and endothelial cell function through epigenetic mechanisms.

3 citations

humanstatistical model

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