LncRNA YIYA enhances pancreatic cancer proliferation under high-glucose conditions through RAS and PKM2 mediated metabolic reprogramming that reinforces the Warburg phenotype
Nachiket Dattatray Garge, Ankita Sharma, Sudeshna Mukherjee, Rajdeep Chowdhury
This study identifies lncRNA YIYA as a glucose-responsive factor in pancreatic cancer that promotes proliferation via RAS and PKM2-mediated metabolic reprogramming, enhancing the Warburg effect.
bioRxiv · Oct 30, 2025 · PreprintCancer Biology