Author

Ajay R. Uprety

Georgetown UniversityORCID 0000-0002-4766-474XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Aelon Ketema Samuel· 1 shared Alexey OstroumoviD· 1 shared Caroline C. SwainiD· 1 shared Daniel J. Reid· 1 shared Helena de Carvalho SchuchiD· 1 shared I. ChangiD· 1 shared Joyce WooiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Aelon Ketema Samuel

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1 paper

Recent·Most cited

Dynamic Changes in Chloride Homeostasis Coordinate Midbrain Inhibitory Network Activity during Reward Learning

Joyce Woo, Ajay R. Uprety, Daniel J. Reid, I. Chang, Aelon Ketema Samuel, Helena de Carvalho Schuch, Caroline C. Swain, Alexey Ostroumov

This study shows that during reward learning, reduced KCC2 in midbrain GABA neurons alters network activity and dopamine responses, essential for forming new reward associations.

Nature Communications · Dec 9, 2025Peer-reviewedNeuroscience