Author

I. Chang

Georgetown UniversityORCID 0009-0005-2088-9622Unclaimed ORCID profile · follow to get notified of new preprints

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I. Chang4 papers

Biology Disciplines

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Neuroscience· 1

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Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Aelon Ketema Samuel· 1 shared Ajay R. UpretyiD· 1 shared Alexey OstroumoviD· 1 shared Caroline C. SwainiD· 1 shared Daniel J. Reid· 1 shared Helena de Carvalho SchuchiD· 1 shared Joyce WooiD· 1 shared

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2025-2025 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Aelon Ketema Samuel

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1 paper

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedDec 9, 2025

Dynamic Changes in Chloride Homeostasis Coordinate Midbrain Inhibitory Network Activity during Reward Learning

Joyce Woo, Ajay R. Uprety, Daniel J. Reid…·Alexey Ostroumov

This study shows that during reward learning, reduced KCC2 in midbrain GABA neurons alters network activity and dopamine responses, essential for forming new reward associations.

3 citations

mouseelectronic health records

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