Author

David A. Nemazee

Scripps Research InstituteORCID 0000-0002-4769-6311Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Changchun XiaoiD· 2 shared Alba Moreno· 1 shared Alicia González-MartíniD· 1 shared Ana M. Prieto-MuñoziD· 1 shared Beatriz Herrero‐FernándeziD· 1 shared Fangkun Luan· 1 shared Jaime L Díaz-VarelaiD· 1 shared Javier SanziD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Changchun XiaoORCID

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2 papers

Recent·Most cited

Lack of Bcl6 promotes anti-tumor immunity by activating glycolysis to rescue CD8 T cell function

Fangkun Luan, Yunqiao Li, Jia Ning, Jenny Tuyet Tran, Tanya R. Blane, Raag Bhargava, Zhe Huang, Changchun Xiao, David A. Nemazee

This study shows that BCL6 deficiency enhances anti-tumor immunity by promoting glycolysis and improving CD8 T cell function in mouse models.

bioRxiv · Apr 1, 2025 · PreprintImmunology

Motif-driven microRNA regulation of B cell tolerance uncovers ERalpha as a female-specific checkpoint

Jaime L Díaz-Varela, Beatriz Herrero‐Fernández, María del Pilar González-Molina, Laura Gámez-Reche, Ana M. Prieto-Muñoz, Javier Sanz, Marina Mendieta-Homs, MariPaz López-Molina, Tania Gonzalo, Alba Moreno, Laura Manas, David A. Nemazee, Changchun Xiao, Laura Otero-Ortega, Alicia González-Martín

This study identifies miR-130b and its GUGCA seed motif as regulators of B cell tolerance, revealing ERalpha as a female-specific checkpoint that influences autoimmunity.

bioRxiv · Jan 22, 2025 · PreprintImmunology