Author

Changchun Xiao

Scripps Research InstituteORCID 0000-0001-8754-3208Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

David A. NemazeeiD· 2 shared Alba Moreno· 1 shared Alicia González-MartíniD· 1 shared Ana M. Prieto-MuñoziD· 1 shared Beatriz Herrero‐FernándeziD· 1 shared Bing XuiD· 1 shared Bowen HouiD· 1 shared Chaonan Yan· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

David A. NemazeeORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintApr 1, 2025

Lack of Bcl6 promotes anti-tumor immunity by activating glycolysis to rescue CD8 T cell function

Fangkun Luan, Yunqiao Li, Jia Ning…·David A. Nemazee

This study shows that BCL6 deficiency enhances anti-tumor immunity by promoting glycolysis and improving CD8 T cell function in mouse models.

DOI 10.1101/2025.04.01.646721

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintFeb 17, 2025

Themis dominates T cell exhaustion by regulation of TCR and PD-1 signaling

Jian Tang, Xian Jia, Taoling Zeng…·Guo Fu

This study shows Themis regulates T cell exhaustion by controlling TCR and PD-1 signaling, with loss of Themis causing severe immunopathology in chronic viral infection.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintJan 22, 2025

Motif-driven microRNA regulation of B cell tolerance uncovers ERalpha as a female-specific checkpoint

Jaime L Díaz-Varela, Beatriz Herrero‐Fernández, María del Pilar González-Molina…·Alicia González-Martín

This study identifies miR-130b and its GUGCA seed motif as regulators of B cell tolerance, revealing ERalpha as a female-specific checkpoint that influences autoimmunity.

DOI 10.1101/2025.01.22.634242

mousebulk RNA-seq

𝕏 PostBluesky