Maturation of the glymphatic system confers innate resistance of the brain to Zika virus infection
Jhulimar Guilherme Doerl, Emanuelly Karine Campos Chaves, Vivian Antonielly Becker dos Santos, Bruna Lorena de Melo Marcelino, Diego Marques Coelho, Leo Morita Miyakoshi, Josélio Maria Galvão de Araújo, Selma M. B. Jerônimo, Eduardo Bouth Sequerra
This study shows that the maturation of the glymphatic system reduces susceptibility to Zika virus infection in mice, suggesting a protective role in the brain.
bioRxiv · Oct 26, 2025 · PreprintNeuroscience