Diego Marques Coelho

The paper uses single-sample network analysis to identify pathogenic hubs in Sjögren's disease and prioritize drug targets.

OrthoGuide provides pre-computed evolutionary rooting data for COGs across eight model species, enabling rapid access to orthology-based evolutionary analysis.

SlytheRINs compares conformational changes in proteins by analyzing residue interaction networks across multiple structures to identify dynamic shifts linked to functional impacts.

This study shows that the maturation of the glymphatic system reduces susceptibility to Zika virus infection in mice, suggesting a protective role in the brain.

The paper identifies Sox9 as a key regulator of neurogenic behavior in radial glial progenitors, showing its role in maintaining stem cell identity and generating upper-layer neurons.

The paper develops a microfluidic co-culture model to study Aβ1-42-induced synaptotoxicity and shows Pyk2 overexpression in postsynaptic neurons protects against it.

This study shows that Neurogenin2 can reprogram Muller glia into retinal ganglion cell-like neurons, with efficiency comparable to ASCL1 but with distinct gene expression outcomes.